"Multi-Threshold Analysis for Chemical Space Mapping of Ni-Catalyzed Suzuki-Miyaura Couplings" LeSueur, A.; Tao, N.; Doyle, A. G.; Sigman, M. Eur. J. Org. Chem., 2024, e202400428. [DOI: 10.1002/ejoc.202400428] Link PDF
"Cooperative Phosphine-Photoredox Catalysis Enables N–H Activation of Azoles for Intermolecular Olefin Hydroamination" Sedillo, K.; Fan, F.; Knowles, R. R.; Doyle, A. G. J. Am. Chem. Soc., 2024, 146, 20349-20356. [DOI: 10.1021/jacs.4c05881] Link PDF
"Mechanism of Ni-Catalyzed Photochemical Halogen Atom-Mediated C(sp3)–H Arylation" Cusumano, A. Q; Chaffin, B. C.; Doyle, A. G. J. Am. Chem. Soc., 2024, 146, 15331-15344. [DOI: 10.1021/jacs.4c03099] Link PDF
"Autonomous closed-loop mechanistic investigation of molecular electrochemistry via automation" Sheng, H.; Sun, J.; Rodríguez, O.; Hoar, B. B.; Zhang, W.; Xiang, D.; Tang, T.; Hazra, A.; Min, D. S.; Doyle, A. G.; Sigman, M. S.; Costentin, C.; Gu, Q.; Rodríguez-López, J.; Liu, C. Nat. Commun, 2024, 15, 2781. [DOI: 10.1038/s41467-024-47210-x] Link PDF
"Data Science Guided Multiobjective Optimization of a Stereoconvergent Nickel-Catalyzed Reduction of Enol Tosylates to Access Trisubstituted Alkenes" Romer, N. P.; Min, D. S.; Wang, J. Y.; Walroth, R. C.; Mack, K. A.; Sirois, L. E.; Gosselin, F.; Zell, D.; Doyle, A. G.; Sigman, M. S. ACS Catal, 2024, 14, 4699-4708. [DOI: 10.1021/acscatal.4c00650] Link PDF
"Identifying general reaction conditions by bandit optimization" Wang, J. Y.; Stevens, J. M.; Kariofillis, S. K.; Tom, M.-J.; Golden, D. L.; Li, J.; Tabora, J. E.; Parasram, M.; Shields, B. J.; Primer, D. N.; Hao, B.; Del Valle, D.; DiSomma, S.; Furman, A.; Zipp, G. G.; Melnikov, S.; Paulson, J.; Doyle, A. G. Nature, 2024,
"Broad Survey of Selectivity in the Heterogeneous Hydrogenation of Heterocycles" Lyons, T. W.; Leibler, I. N.-M.; He, C. Q.; Gadamsetty, S.; Estrada, G. J.; Doyle, A. G. J. Org. Chem. 2024, 89, 1438-1445. [DOI: 10.1021/acs.joc.3c02028] Link PDF
The Doyle Lab • Prof. Abigail Doyle
Saul Winstein Chair in Organic Chemistry
Department of Chemistry and Biochemistry, UCLA
3515 Molecular Science Building • Los Angeles, CA 90095
abigaildoyle@g.ucla.edu • Phone: (310) 206-1036
