Using Data Science to Guide Aryl Bromide Substrate Scope Analysis in a Ni/Photoredox-Catalyzed Cross-Coupling with Acetals as Alcohol-Derived Radical Sources

Stavros, Shutian, Andrzej, Shivanni, and Jesus’ paper on a Ni/photoredox-catalyzed (deutero)methylation and alkylation of aryl halides with integration of data science techniques to quantify population-wide reactivity trends was recently published in JACS. A great team effort!

Using Data Science to Guide Aryl Bromide Substrate Scope Analysis in a Ni/Photoredox-Catalyzed Cross-Coupling with Acetals as Alcohol-Derived Radical Sources2023-02-16T11:36:02-08:00

A general strategy for C(sp3)–H functionalization with nucleophiles using methyl radical as a hydrogen atom abstractor

Izzy and Makeda’ work on developing a sequential hydrogen atom transfer and oxidative radical-polar crossover strategy that transforms C(sp3)–H bonds into carbocations functionalized by a variety of nucleophiles was published in Nature Communications. Great work and congratulations!

A general strategy for C(sp3)–H functionalization with nucleophiles using methyl radical as a hydrogen atom abstractor2023-02-17T14:31:04-08:00
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