107. "Transferable enantioselectivity models from sparse data" Gallarati, S.; Bucci, E. M.; Doyle, A. G.; Sigman, M. S. Nature, Accelerated Preview. [DOI: 10.1038/s41586-026-10239-7] Link PDF
105. "Development, Application, and Mechanistic Interrogation of a Dual Ni Catalysis Approach to Photoredox-Based C(sp3)–C(sp3) Cross-Coupling" Bucci, E. M.; Perea, M. A.; Lalisse, R. F.; Mukherjee, P.; Raab, T. J.; Kannadi Valloli, L.; Min, D. S.; Bird, M. J.; Gutierrez, O.; Doyle, A. G. J. Am. Chem. Soc., 2025, 147, 42311–42329. [DOI: 10.1021/jacs.5c11247] Link PDF
"Reactivity Studies of Bipyridine-Ligated Nickel(I) and Nickel(0) Complexes Inform the Mechanism in Modern Cross-Coupling Reactions" Raab, T. Judah.; Doyle, A. G. J. Am. Chem. Soc., 2025, 147, 33991–34000. [DOI: 10.1021/jacs.5c11247] Link PDF
"Light-Promoted C(sp³)–C(sp³) Reductive Elimination from Dialkyl Ni(II) Complexes" Cusumano, A. Q.; Chaffin, B. C.; Cagan, D. A.; DiLuzio, S.; Sutcliffe, E.; Hadt, R. G.; Doyle, A. G. J. Am. Chem. Soc., 2025, 147, 32941–32950. [DOI: 10.1021/jacs.5c09925] Link PDF
"Ni-Catalyzed Reductive Coupling of Acetals with Anhydrides and Vinyl Triflates via Single-Electron C–O Activation" Kim, E.; Borden, M. A.; Hwang, J.; Doyle, A. G.; Dongbang, S. Org. Lett., 2025, 27, 9454–9459. [DOI: 10.1021/acs.orglett.5c02788] Link PDF
"Applying Active Learning toward Building a Generalizable Model for Ni-Photoredox Cross-Electrophile Coupling of Aryl and Alkyl Bromides" Souza, L. W.; Ricke, N. D.; Chaffin, B. C.; Fortunato, M. E.; Jiang, S.; Soylu, C.; Caya, T. C.; Lau, S. H.; Wieser, K. A.; Doyle, A. G.; Tan, K. L. J. Am. Chem. Soc., 2025, 147, 18747-18759.
"Multi-Threshold Analysis for Chemical Space Mapping of Ni-Catalyzed Suzuki-Miyaura Couplings" LeSueur, A.; Tao, N.; Doyle, A. G.; Sigman, M. Eur. J. Org. Chem., 2024, e202400428. [DOI: 10.1002/ejoc.202400428] Link PDF
"Mechanism of Ni-Catalyzed Photochemical Halogen Atom-Mediated C(sp3)–H Arylation" Cusumano, A. Q; Chaffin, B. C.; Doyle, A. G. J. Am. Chem. Soc., 2024, 146, 15331-15344. [DOI: 10.1021/jacs.4c03099] Link PDF
"Data Science Guided Multiobjective Optimization of a Stereoconvergent Nickel-Catalyzed Reduction of Enol Tosylates to Access Trisubstituted Alkenes" Romer, N. P.; Min, D. S.; Wang, J. Y.; Walroth, R. C.; Mack, K. A.; Sirois, L. E.; Gosselin, F.; Zell, D.; Doyle, A. G.; Sigman, M. S. ACS Catal, 2024, 14, 4699-4708. [DOI: 10.1021/acscatal.4c00650] Link PDF
"Catalyst Deactivation of a Monoligated CyJohnPhos-Bound Nickel(0) Complex" Newman-Stonebraker, S. H.; Raab, T. J.; Doyle, A. G. Organometallics 2023, 42, 3438-3441. [DOI: 10.1021/jacs.3c08301] Link PDF
The Doyle Lab • Prof. Abigail Doyle
Saul Winstein Chair in Organic Chemistry
Department of Chemistry and Biochemistry, UCLA
3515 Molecular Science Building • Los Angeles, CA 90095
abigaildoyle@g.ucla.edu • Phone: (310) 206-1036
