Welcome New Doyle Lab Members!
We welcome to the lab four first years, Maddy, Erin, Judah, and Daniel! We’re happy to have you in the group and excited for all your future research endeavors.
A general strategy for C(sp3)–H functionalization with nucleophiles using methyl radical as a hydrogen atom abstractor
Izzy and Makeda’ work on developing a sequential hydrogen atom transfer and oxidative radical-polar crossover strategy that transforms C(sp3)–H bonds into carbocations functionalized by a variety of nucleophiles was published in Nature Communications. Great work and congratulations!
A biohybrid strategy for enabling photoredox catalysis with low-energy light
Stephen and Jesus’ paper on developing a biohybrid photocatalyst to perform thiol-ene coupling and cysteinyl-desulfurization reactions was recently published in Chem. Congrats to the whole team!
The Evolution of Data-Driven Modeling in Organic Chemistry
Wendy's recent outlook article detailing the history and current state of the field of data-driven modeling in organic chemistry has been published in ACS Central Science. Congrats to Wendy and her collaborators in the Sigman and Anslyn labs on a
Phosphine/Photoredox Catalyzed Anti-Markovnikov Hydroamination of Olefins with Primary Sulfonamides via α-scission from Phosphoranyl Radicals
Kassandra and Alex's work using phosphine and photoredox catalysis to perform hydroamination of olefins via α-scission of phosphoranyl radicals was recently published in JACS. Nice work and congrats to all!
Univariate Classification of Phosphine Ligation State and Reactivity in Cross-Coupling Catalysis
Sam and Julia's recent work classifying phosphine ligation state in cross-coupling reactions on the basis of a conformer-specific buried volume parameter has been published in Science. Congratulations to the whole Doyle, Sigman, and Merck phosphine team!
