Continuous flow synthesis of pyridinium salts accelerated by multi-objective Bayesian optimization with active learning
Congratulations to Jose and our collaborators at the Air Force Research Laboratories on their publication!
Comparison of Monophosphine and Bisphosphine Precatalysts for Ni-Catalyzed Suzuki–Miyaura Cross-Coupling: Understanding the Role of the Ligation State in Catalysis
Congratulations to Julia and Sam on their publication!
Strategies for Nucleophilic C(sp3)–(Radio)Fluorination
Congratulations to Izzy, Shivaani, and Makeda on their publication!
Interrogating the Mechanistic Features of Ni(I)-Mediated Aryl Iodide Oxidative Addition Using Electroanalytical and Statistical Modeling Techniques
Congratulations to Daniel, Wendy, and their Sigman group collaborators on their publication!
A Machine Learning Approach to Model Interaction Effects: Development and Application to Alcohol Deoxyfluorination
Congratulations to Andrzej and Shivaani on their publication!
On the use of real-world datasets for reaction yield prediction
Congratulations to Andrzej and collaborators on their publication!
Radical Redox Annulations: A General Light-Driven Method for the Synthesis of Saturated Heterocycles
Izzy’s paper on a general two-component annulation strategy that provides access to a diverse collection of five- and six-membered saturated heterocycles was published in ACS Catalysis. Great work and congratulations!
A Multi-Objective Active Learning Platform and Web App for Reaction Optimization
Jose and Will’s work on the development of an open-source experimental design via Bayesian optimization platform (EDBO+) for multi-objective reaction optimization was recently published in JACS. (https://www.edbowebapp.com/) Congratulations!
Ni/Photoredox-Catalyzed C(sp3)–C(sp3) Coupling between Aziridines and Acetals as Alcohol-Derived Alkyl Radical Precursors
Sun’s paper on a novel Ni/photoredox methodology for C(sp3)–C(sp3) cross-coupling between aziridines and aliphatic alcohols activated as benzaldehyde dialkyl acetals was published in JACS. Congratulations!
Structure–Reactivity Relationships of Buchwald-Type Phosphines in Nickel-Catalyzed Cross-Couplings
Sam and Jason’s work on elucidating structure–reactivity relationships of Buchwald-type phosphines in Ni-catalyzed cross-coupling reactions was recently published in JACS. Congratulations!
